Intended
Use: The Tetracore RedLine
Alert™ Test is an immunochromatographic test intended for the
rapid, in vitro qualitative presumptive identification of Bacillus
anthracis from non-hemolytic Bacillus colonies cultured
on sheep blood agar plates. The test is intended for use in clinical,
public health, and hospital laboratories in conjunction with other markers
and testing for the presumptive identification of Bacillus anthracis.
Easy to use and easy to interpret so you can accelerate the “can’t
rule out” process.
On a non-hemolytic Bacillus , if the RedLine
Alert™ Test is
positive, then B. anthracis can’t be ruled out. Submit
the sample to the appropriate State Lab for confirmation.
RedLine Alert™ gives sentinel labs the ability to significantly shorten
the time from when the plate is streaked until PCR confirmation is
completed at the LRN reference lab.
Superior to gamma phage lysis when tested against 145 extremely well-characterized,
independent, genetically and geographically diverse B.
anthracis isolates,
from 28 countries covering all major diversity groups: Ames-Sterne,
Vollum, Western North America, Southern Africa, and Kruger.
- RedLine Alert™ Test: 98.6% correct
- Gamma Phage Lysis: 97.2% correct
The two false negative results with the RedLine Alert™ Test
and the four false negative results with gamma phage lysis did not
coincide, thus emphasizing that utilization of more than one detection
method can aid in the identification of B. anthracis
No false positives (i.e. 100% correct negatives) test results
with 49 non-hemolytic Bacillus spp, (other than B.
anthracis).
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